The mosaic masks were created in 3DSMax, then brought in to Substance Designer for placement, compositing, wear, etc..
I painstakingly traced all the mosaic tiles in the center of the reference image using the Shapes function in 3DSMax since you can't get this sort of organic tile layout in Substance Designer.
I used that intertwined swirly pattern on another mosaic, so I used a simpler triangular mosaic trim.